Process Engineering Design

for biotech

Allen Associates is one of Scotland’s leading chemical and process engineering consultancies, providing specialist engineering support to the biotechnology, fermentation and industrial bioprocess sectors.

Our team has extensive experience developing fermentation-based manufacturing facilities, biofuel plants, solvent recovery systems, utility infrastructure and downstream processing operations. We support clients throughout the project lifecycle, from early-stage feasibility and business case development, through FEED studies and supporting investor-grade cost estimating, to detailed design, construction support, commissioning and operational optimisation.

Recent projects include major engineering support for Celtic Renewables’ Project Catkin, where Allen Associates provided process engineering, Aspen Plus modelling, solvent recovery system optimisation, hygienic design development, CIP/SIP strategy, process safety studies, equipment specification and FEED delivery for a commercial-scale biofuels facility.

Combining practical project delivery experience with rigorous engineering analysis, we develop solutions that are technically robust, commercially viable and capable of withstanding the scrutiny of investors, funding bodies and regulatory stakeholders.

biotech plans
biotech plant render

Typical services include:

Feasibility & Concept Development

  • Concept design and feasibility studies
  • Process development and technology scale-up support
  • Process flow diagrams (PFDs)
  • Heat and material balances
  • Fermentation process evaluation
  • Aspen Plus process modelling and simulation
  • Solvent Recovery System (SRS) modelling and optimisation
  • Evaluation of alternative process configurations
  • Utility demand assessments
  • Site master planning and facility layout studies
  • CAPEX and OPEX forecasting
  • Support investor grade cost estimates
  • Preliminary risk, SHE and regulatory assessments

Detailed Engineering & Design

  • Piping and Instrumentation Diagrams (P&IDs)
  • Hygienic process design
  • Sterile boundary definition and management
  • Clean-in-Place (CIP) system design
  • Steam-in-Place (SIP) system design
  • Equipment sizing, specification and procurement support
  • Bioreactor, fermenter and downstream process integration
  • Solvent Recovery System (SRS) specification and optimisation
  • Utility system design including steam, chilled water, cooling water, compressed air, nitrogen and clean utilities
  • 3D plant layout and process modelling
  • Process control philosophies
  • Pressure systems and relief design
  • Process safety studies including HAZOP, LOPA and DSEAR
  • Design QA and technical sign-off
  • Regulatory compliance support
  • Investor scrutiny support

Project Delivery & Implementation

  • Budget development and CAPEX management
  • Preparation of tender documentation and bid evaluations
  • Procurement support and vendor management
  • Detailed project planning and coordination
  • Construction, installation and commissioning support
  • Technical query management
  • Factory and site acceptance testing
  • Start-up and process optimisation support
  • Operator training
  • Performance verification and process troubleshooting
  • Handover documentation and ongoing operational support

Clients often tell us that Allen Associates hits a “sweet spot” in the market. We combine the technical capability and engineering rigour needed to deliver large-scale biotechnology and fermentation projects with the responsiveness, flexibility and personal service of a specialist consultancy.

This allows us to develop practical, commercially focused solutions that are appropriately engineered for the project, helping clients maximise value from their investment while still meeting the expectations of investors, funders and regulatory stakeholders.

celtic renewables logo
mialgae logo
rothes corde logo

Our Clients

While best known for our work with major brands in the world of distilled spirits our involvement in the bio-tech sector continues to go from strength to strength. This includes working with Celtic Renewables, MiAlgae, and Rothes Corde Ltd, on innovative projects where our understanding of fermentation, separation, heat integration, Aspen Modelling and co-product handling has added significant value to their business.

Jump to Top